First of all some of the Nicholson files made these days are cases hardened and are thus unsuitable for knife making. If you have a file that is made from high carbon steel then drawing the temper in the file and then making a blade from it can work, I just don't know if I would go all the way up to 450°, I think that I would stop at 400° to keep a bit more hardness in it for the finished blade. It will be harder and slower to grind the blade and you will need to cool often to keep from drawing the temper further when grinding. It's basically the same thing as when some makers like to harden and temper thin blades before grinding the bevels.
Doug